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  • What is prostate cancer?

    Contents

    The prostate

    The prostate is a small gland that sits below the bladder. The gland, which is about the size of a walnut, is part of the reproductive system. Only men have a prostate gland.

    The prostate gland produces fluid that helps to feed and protect sperm. This fluid is the main component of semen.

    The urethra runs through the prostate gland. The urethra is a thin tube that carries urine from the bladder through the penis. It also carries semen from the prostate and testicles out of the body during orgasm.

    The prostate gland is surrounded by muscle which enables it to contract and produce ejaculate. It is located near nerves, blood vessels and muscles that are needed to control bladder function and to achieve an erection.

    The growth of the prostate depends on the male sex hormone, testosterone which is made by the testicles (testes). It is normal for the prostate to increase in size as men age. Sometimes this can cause problems, especially with urination.

    Prostate problems

    It is very common for men over 50 to experience one or more of the following:

    • a need to urinate more often
    • a frequent, urgent need to urinate
    • difficulty starting the flow
    • a slow or stop-start stream
    • leaking or dribbling after urinating.

    In most cases these symptoms are caused by a non-cancerous, enlarged prostate—a common problem in men as they age. An enlarged prostate does not lead to prostate cancer. However speak to your GP if you have any of these symptoms.

    What is prostate cancer?

    Prostate cancer develops when abnormal cells in the prostate gland start to grow more rapidly than normal cells, and in an uncontrolled way. Most prostate cancers grow more slowly than other types of cancer although this is not always the case.

    Early (or localised) prostate cancer means cancer cells have grown but, as far as it is possible to tell, have not spread beyond the prostate.

    There are two stages of advanced prostate cancer. If the cancer grows and spreads outside the prostate gland into the seminal vesicles (glands that lie close to the prostate) or nearby parts of the body, such as the bladder or rectum, it is called locally advanced prostate cancer. Metastatic prostate cancer is when the cancer has spread to distant parts of the body such as the lymph glands or bones.

    Symptoms of prostate cancer

    Early prostate cancer rarely causes symptoms. Even with advanced prostate cancer there may be no symptoms. Where symptoms do occur they are often due to non-cancerous conditions such as benign prostate hyperplasia (BPH).

    Symptoms of advanced prostate cancer may include unexplained weight loss, feeling the frequent or sudden need to urinate, or pain in the lower back/pelvic area or sciatica.

    These are not always a sign of prostate cancer but you should speak with a doctor if you have any of these symptoms.

    Risk factors for prostate cancer

    While the causes of prostate cancer are unknown your risk of developing prostate cancer increases:

    • as you get older – prostate cancer is mainly diagnosed in men aged 60–79
    • if your father or brother has had prostate cancer – your risk is twice that of other men
    • if you have a strong family history of breast or ovarian cancer, particularly BRCA1 and BRCA2 gene mutations.

    While prostate cancer is rare in men under 50, men aged 45–55 are at particular risk of developing significant prostate cancer later in life if their prostate specific antigen (PSA) test results are above the 95th percentile. This means that PSA levels are higher than 95% of men in the same age range.

    You may have an inherited gene that increases your risk of prostate cancer if you have:

    • multiple relatives on the same side of the family (either your mother’s or father’s side) with prostate, breast and/or ovarian cancers
    • a male relative under the age of 50 with prostate cancer.

    If you are concerned about your family history, your GP can advise you on the suitability of PSA testing for you and your family. For more information call Cancer Council 13 11 20.

    This website page was last reviewed and updated April 2017.

    Information last reviewed April 2016 by: A/Prof Nicholas Brook, Consultant Urological Surgeon, Royal Adelaide Hospital and Clinical Associate Professor in Surgery, University of Adelaide, SA; Prof Ian Davis, Professor of Medicine and Head of Eastern Health Clinical School, Monash University and Senior Oncologist, Eastern Health, VIC; A/Prof David Smith, Senior Research Fellow and Cancer Epidemiologist, Cancer Council NSW, NSW; A/Prof Peter Reaburn, Associate Professor in Exercise and Sport Sciences, CQU, QLD; Sylvia Burns, Senior Cancer Specialist, Cancer Council Queensland, QLD; Robyn Tucker, Clinical Nurse Specialist, Cancer Information and Support, Cancer Council Victoria, VIC.

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