MicroRNAs are vital regulators of all cellular processes, including cancer. Up until now, almost all reports of microRNAs exclusively look at their role within the cytoplasm.
New information however suggests there may also be far more extensive roles for microRNAs within the nucleus. Thus, important roles may have gone unnoticed.
We are seeking to understand this new role for microRNAs in the nucleus in order to better understand how they act to both promote and inhibit cancer progression.