GSK Breast

This is a combination Phase I and Phase II study, with an aim to evaluate the combination ofGSK 525762 and fulvestrant in women with HR+/HER2- advanced or metastatic breast cancer, who have disease that has progressed after prior treatment with at least one line of endocrine therapy. GSK525762 and fulvestrant in women with HR+/HER2- advanced or metastatic breast cancer, who have disease that has progressed after prior treatment with at least one line of endocrine therapy.

Acronym:

GSK Breast

ACTRN/NCT /ethics:

NCT02964507

Scientific title:

A phase I/II dose escalation and expansion study to investigate the safety, pharmacokinetics, pharmacodynamics and clinical activity of GSK525762 in combination with fulvestrant in subjects with ER+ breast cancer

Sponsor / Cooperative group:

GlaxoSmithKline