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Trial Summary

Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer



ACTRN/NCT /ethics:


Scientific title:

An open-label, randomized, controlled phase 3 study of enfortumab vedotin in combination with pembrolizumab versus chemotherapy alone in previously untreated locally advanced or metastatic urothelial cancer.

Sponsor / Cooperative group:

Astellas Pharma Global Development, Inc.

Trial & Patient Characteristics

Cancer TypeOther
Trial TypeTreatment
PhasePhase III
Age Range18 years and older
Tumour Stream Urothelial
Cancer StageLocally Recurrent or Locally Advanced; Metastatic or Widespread
Anticipated Start Date2020-03-30
Anticipated End Date2023-11-22

Participating Hospitals

HospitalLyell McEwin Hospital
Clinical Trial CoordinatorAndy Phay
Phone08 8282 0833
Principal InvestigatorDr Mark McGregor
Recruitment StatusRecruiting