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  • SPAR

    Acronym: 

    SPAR

    ACTRN/NCT /ethics: 

    ACTRN12617001087347

    Scientific title: 

    A clinical trial comparing Simvastatin to placebo, in addition to standard chemotherapy and radiotherapy, in preoperative treatment for patients with rectal cancer. | SPAR

    Summary of trial and patient characteristics

    Cancer Type Bowel and colon
    Trial Type Treatment
    Phase Phase II Tumour Stream Rectal
    Age Range 18 years and older Cancer Stage All stages
    Sex Both Anticipated Start Date 2017-10-02
    Molecular Target Anticipated End Date 2020-10-02
    Cancer Type Bowel and colon
    Trial Type Treatment
    Phase Phase II
    Age Range 18 years and older
    Sex Both
    Molecular Target
    Tumour Stream Rectal
    Cancer Stage All stages
    Anticipated Start Date 2017-10-02
    Anticipated End Date 2020-10-02

    Trial Summary

    The primary purpose of this trial is to compare the effect of simvastatin with placebo on the effectiveness and side effects of pre-operative chemoradiotherapy treatment prior to rectal cancer surgery, and on the body's inflammatory response to cancer.

    Lay Summary

    A clinical trial comparing Simvastatin to placebo, in addition to standard chemotherapy and radiotherapy, in preoperative treatment for patients with rectal cancer. | SPAR

    Sponsor / Cooperative group

    AGITG

    Participating Hospitals

    Hospital Clinical Trial Coordinator Email Phone Principal Investigator Recruitment Status
    The Queen Elizabeth Hospital Pamela Cooper pamela.cooper@sa.gov.au 08 8222 6410 Professor Tim Price Recruiting
    Flinders Medical Centre Alex Scott-Hoy alex.scott-hoy@sa.gov.au 08 8204 4830 Dr Chris Karapetis Not Yet Recruiting