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  • RTN2

    Acronym: 

    RTN2

    ACTRN/NCT /ethics: 

    NCT00975520

    Scientific title: 

    Neurotropic Melanoma of the Head and Neck

    Summary of trial and patient characteristics

    Cancer Type Melanoma & other skin
    Trial Type Treatment
    Phase All phases Tumour Stream Melanoma of head and neck
    Age Range 18 years and older Cancer Stage All stages
    Sex Both Anticipated Start Date 2009-09-01
    Molecular Target Anticipated End Date 2020-02-01
    Cancer Type Melanoma & other skin
    Trial Type Treatment
    Phase All phases
    Age Range 18 years and older
    Sex Both
    Molecular Target
    Tumour Stream Melanoma of head and neck
    Cancer Stage All stages
    Anticipated Start Date 2009-09-01
    Anticipated End Date 2020-02-01

    Trial Summary

    This is a 2-armed randomised controlled trial comparing surgery alone with surgery plus post-operative radiation therapy for patients with completely resected primary melanoma showing histological features of neurotropism. Uncontrolled studies suggest that this form of primary melanoma has a high risk of local recurrence and that postoperative radiation therapy may substantially reduce that risk. Patients who are eligible on the basis of the pathology of the excised melanoma will be offered the opportunity to take part in the trial. Those randomised to receive radiation therapy will be treated with a simple technique encompassing the surgical bed plus a margin. Radiation will commence within 3 months of surgery (maximum of 14 weeks from surgery to start of radiotherapy).

    Lay Summary

    Neurotropic Melanoma of the Head and Neck

    Sponsor / Cooperative group

    Melanoma and Skin Cancer Trials Limited

    Participating Hospitals

    Hospital Clinical Trial Coordinator Email Phone Principal Investigator Recruitment Status
    Royal Adelaide Hospital Anne Milton anne.milton@sa.gov.au 08 7074 2342 Professor Hui Tee Recruiting