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Staging, grading and prognosis of uterine cancer


Staging is a way to describe the size of the cancer and whether it has spread to other parts of the body.

stage IThe cancer is found only in the uterus - early or localised cancer.
stage II The cancer has spread from the uterus to the cervix - regionalised cancer.
stage IIIThe cancer has spread beyond the uterus/cervix to the ovaries, fallopian tubes, vagina, or lymph nodes in the pelvis or abdomen - regionalised cancer.
stage IVThe cancer has spread further, to the bladder or rectum, throughout the abdomen, to other parts of the body such as the bones or lung, or to lymph nodes in the groin - metastatic or advanced cancer.


Grading describes how the cancer cells look under a microscope compared to normal cells and how aggressive they may be.

grade 1 (low grade)The cancer cells look slightly abnormal.
grade 2 (moderate grade)The cancer cells look moderately abnormal.
grade 3 (high grade)The cancer cells look more abnormal. These cancers tend to be more aggressive than lower-grade cancers.


Prognosis means the expected outcome of a disease. You may wish to discuss your prognosis and treatment options with your oncologists. However, it is not possible for anyone to predict the exact course of the disease in an individual person. Instead, your doctor can give you an idea about the general outlook for people with the same type and stage of cancer. You will also have tests to check how the cancer is responding to treatments.

Test results, the type of uterine cancer, the rate and depth of tumour growth, the likelihood of response to treatment, and factors such as your age, level of fitness, and medical history are all important in assessing your prognosis. As for most types of cancer, the outcomes tend to be better when uterine cancer is found and treated early.